Loading and saving raw images

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I'm looking to be able to read in pixel values as captured in a raw NEF image, process the data for noise removal, and then save the new values back into the raw image format maintaining all the metadata for later use. I've seen dcraw can read in raw format and output the Bayer pattern data as a tiff or other image but I can't save it back to my NEF. I've also been attempting to read in and save the image with simple python file open or numpy memmap but have no clue how to handle the binary data. Any help would be appreciated. Thanks!

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