We just recently disabled other protocols and enabled TLS 1.2 only. After doing so, the TwitterApp that posts tweets suddenly was not functioning properly. I suspect that the third party library was using SSL or lower versions of tls.
The Application was created using c# and is using Twitterizer2.dll.
Hi Have you try to set this in your POST REQUEST?
System.Net.ServicePointManager.SecurityProtocol = SecurityProtocolType.Tls12;