I tested this with python 3.5 in Debian Stretch.
I tried benchmark the "Avoiding dots" optimization.
As expected, the "Avoiding dots" optimization is really much faster.
Unexpected, timeit reports the slower code as the faster.
What is the reason?
$ time python3 -m timeit -s "s=''" "s.isalpha()"
10000000 loops, best of 3: 0.119 usec per loop
real 0m5.023s
user 0m4.922s
sys 0m0.012s
$ time python3 -m timeit -s "isalpha=str.isalpha;s=''" "isalpha(s)"
1000000 loops, best of 3: 0.212 usec per loop
real 0m0.937s
user 0m0.927s
sys 0m0.000s
timeit
did 10 times as many iterations in the “slow” case. It adaptively tries more iterations to find a number that balances statistical quality and waiting time.