inbreeding coefficient calculation and genealogical software

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I am currently looking for a piece of software which will be able to map a very large number of GEDCOM files (for around 33,000 individuals) as well as working out ancestral and individual inbreeding coefficients. Does anyone know of any software which is capable????

Thanks

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0
1.01pm On

You might be interested in Pypedal Python Pedigree Analysis which is a Python module that provides tools for the manipulation of pedigrees, simple visualization of pedigrees, and the calculation of measures of genetic diversity from pedigrees.

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mwhite On

GeneWeb (written in ML) handles large files very well and has fast consanguinity coefficient computing. I believe it calculates the consanguinity coefficient for every individual in the database upon import, and it does this within a couple seconds. It also displays arbitrarily deep ancestry and descendant trees without any noticeable lag.

http://cristal.inria.fr/~ddr/GeneWeb/en/index.html#Par

It can also handle an arbitrary number of GEDCOMs.

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Jay Askren On

I don't think you will find any software that does this for you, but it wouldn't be too difficult to write your own. I would take one of the many open source gedcom parsers out there and add the individuals to a graph database such as Neo4j. Once it is in Neo4j, it should be relatively easy to run your calculations on the individuals.