Get all grid values on a diagonal line from point to point in xarray

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I'm looking to select all data from an xarray dataset that is between one point and another. This is of course easy with sel for example with a dataset based on a lat/lon grid to subset from a global dataset to the Atlantic coastline I can do ds_geo_subset = ds.sel( lat=slice(42, 20), lon=slice(-85,-65)) but I want to select all data along the Gulf Stream front, basically from to point (-78 lon, 32 lat) to (-72 lon, 36 lat) but I'm not sure how to do this. Would this be best done by giving a full point dataset and getting data from each point or can these two end points be given to xarray and interpolated data returned?

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As the comment above suggested, Metpy has a specific function which can be handy for this task.

from metpy.interpolate import cross_section

data = xr.open_dataset('my_data')

# Define start and end points:

start = (-78, 32)
end = (-72, 36)
cross = cross_section(data, start, end).set_coords(('lat', 'lon'))

Here is a nice example to plot a cross-section.