I'm with a problem to use ElastiCache nodes with Magento, because I'm not able to configure Autodiscovery merged with Magento.
Is possible to configure Magento just with the Host of the ElastiCache Cluster and use all the nodes simultaneously? (just as a cluster)
Yes. In the Elasticache console, click on Replication Groups, then pick your cluster from the list. Find the value for Primary Endpoint and use that as your cache host. This will point at the cluster and will properly handle node failover.